Studies on the Pathogenesis of Influenzal Pneumonitis. Intranasal Vs. Intravenous Infection of Mice †‡

Comparison of host resistance to primary and secondary Listeria monocytogenes infections in mice by intranasal and intravenous routes.

There have been no studies on the susceptibility and host immune responses to an intranasal infection with Listeria monocytogenes. In this study, we compared the susceptibilities and cytokine responses between intranasal and intravenous infections with L. monocytogenes in mice. Moreover, we compared efficiency of acquisition of host resistance to L. monocytogenes infection between intranasally ...

Pulmonary infection of adult white mice with the TE 55 strain of trachoma virus.

Thygeson & Nataf (1958) stated, ‘It is now generally agreed that only primates are susceptible to experimental infection with trachoma virus ’. Since then Giroud, Renoux & Nataf (1958) have reported pulmonary hepatization in mice after intranasal inoculation of material from trachomatous conjunctivae; Hurst & Reeve (1960) reported passage of the TE55 strain in mouse brain; and Bernkopf (1959) r...

Intranasal treatment of cowpox virus respiratory infections in mice with cidofovir.

Orthopoxvirus infections in mice have been effectively treated with cidofovir, a clinically approved drug given by intravenous infusion to treat cytomegalovirus infections. In a bioterrorist scenario it would be technically difficult to give this drug to a large number of exposed individuals. New treatment approaches are being sought, which include giving cidofovir by alternative routes or desi...

Comparison of the effectiveness of intranasal ketamine compared with intravenous ketamine in controlling pain during cataract surgery

Pathway Analysis of miRNA-1 and Its Expres-sion Evaluation in Donor’s Serum from HIV-Positive Individuals vs Unaffected Controls

Background MicroRNAs (miRNAs) are non-coding RNA molecules (19-24 nucleotides) that play a major role in a wide range of biological processes through post-transcriptional regulation of gene expression. Differential expression of miRNAs has been reported in various infectious diseases such as HIV infection. The characterization of miRNA expression profiles, especially in mammalian biofluids, whi...